Cardiology News / Recent Literature Review / Last Quarter 2020
Rhythmos 2021;16(1): 102-109.
26th Annual International AF Virtual Symposium, 29-31/1/2021
EHRA online Congress, 23-25/4/2021
ACC Meeting: Atlanta, 15-17/5/2021
EuroPCR online, 18-20/5/201
ESC Digital Congress 27-30/8/2021
TCT Meeting, San Francisco, 22-26/10/2021
Active Myocardial Inflammation is a Powerful Predictor of Recurrent Ventricular Tachycardia (VT) Following Catheter Ablation: VT Ablation Should be Avoided During Active Myocarditis (AM), But is Often of Benefit for Recurrent VT After the Acute Phase of Myocarditis
Among 125 consecutive patients (age 51±14 years, 91% men, LVEF 52%±9%) with myocarditis diagnosed by endomyocardial biopsy (59%) and/or cardiac magnetic resonance (90%), undergoing VT ablation, with all patients showing low-voltage areas (LVA) at electro-anatomical map (97% epicardial or endoepicardial), VT recurrences were documented in 25 patients (20%) by 12 months, and in 43 (34%) by last follow-up (median 63 months). At multivariable analysis, active myocarditis (AM) stage was the only predictor of VT recurrences by 12 months (hazard ratio: 9.5; p < 0.001), whereas both AM stage and wide border zone were associated with arrhythmia recurrences anytime during follow-up. No VT episodes were found after redo ablation was performed in 23 patients with previous (non-active) myocarditis (Peretto G et al, J Am Coll Cardiol 2020;76:1644–1656).
Left Ventricular (LV) Non-Compaction (LVNC): Vigorous Recreational Physical Activity (VPA) May be a Possible Determinant of LV Hypertrabeculation in Asymptomatic Individuals
In PESA (Progression of Early Subclinical Atherosclerosis) study participants (n = 4,184 subjects free of cardiovascular disease), LVNC phenotype prevalence according to the Petersen criterion was significantly higher among participants in the highest VPA quintile (Q5 = 30.5%) than in participants with no VPA (14.2%). The Jacquier and Grothoff criteria were also more frequently fulfilled in participants in the highest VPA quintile (Jacquier Q5 = 27.4% vs no VPA = 12.8% and Grothoff Q5 = 15.8% vs no VPA = 7.1%). The prevalence of the systolic Stacey LVNC criterion was low (3.6%) and did not differ significantly between no VPA and Q5 (de la Chica JA et al, J Am Coll Cardiol 2020;76: 1723–1733).
Interleukin-1β (IL-1β) Measured on Admission is Associated with Risk of Premature Death in Patients with Myocardial Infarction
IL-1β concentration measured at admission in 1,398 patients with ST-segment elevation MI (STEMI) was associated with all-cause mortality at 90 days (adjusted hazard ratio - adjHR: 1.47 per 1 SD increase; p < 0.002). The relation was nonlinear, and the highest tertile of IL-1β was associated with higher mortality rates at 90 days (adjHR: 2.78; p = 0.0002) and at 1 year (adjHR: 1.93; p = 0.005), regardless of the hs-CRP concentration. Significant relationships were equally observed when considering cardiovascular mortality and MACEs at 90 days (adjHR: 2.42; p = 0.002, and adjHR: 2.29; p = 0.004, respectively) and at 1 year (adjHR: 2.32; p = 0.002, and adjHR: 2.35; p = 0.001, respectively) (Silvain J et al, J Am Coll Cardiol 2020;76:1763–1773)... (excerpt)
Authors who publish with this journal agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).