CABANA Trial: The Aftermath after the Negative / Neutral Results

Antonis S Manolis


The results of the CABANA trial were recently presented at the Heart Rhythm Society Meeting in May 2018, indicating that ablation in patients with atrial fibrillation (AF) did not confer a benefit over drug treatment in the intention-to treat analysis, but did so in an on-treatment analysis. The presentation stirred commotion in the medical community with fierce controversy appearing in the media, mostly related to an apparent willingness of electrophysiologists to dispel the first and accept the second type of analysis. Rhythmos 2018;13(3): 45-47.


atrial fibrillation; catheter ablation; pulmonary vein isolation; antiarrhythmic drug therapy

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